Antoine coefficients in the form log10(P in bar) = A - B / (T in K + C), with the temperature range each fit is valid over. Use them to predict a solvent’s vapour pressure, or the bath temperature a rotary evaporator needs at a given pressure.
| Compound | Formula | A | B | C | Valid T (K) |
|---|---|---|---|---|---|
| Water | H2O | 4.65430 | 1435.264 | -64.848 | 255.9 to 373.0 |
| Methanol | CH4O | 5.20409 | 1581.341 | -33.500 | 288.1 to 356.8 |
| Ethanol | C2H6O | 5.24677 | 1598.673 | -46.424 | 292.8 to 366.6 |
| Acetone | C3H6O | 4.42448 | 1312.253 | -32.445 | 259.2 to 507.6 |
| Dichloromethane | CH2Cl2 | 4.53691 | 1327.016 | -20.474 | 233.0 to 313.0 |
| Chloroform | CHCl3 | 4.20772 | 1233.129 | -40.953 | 215.0 to 334.4 |
| Ethyl acetate | C4H8O2 | 4.22809 | 1245.702 | -55.189 | 288.7 to 349.0 |
| n-Hexane | C6H14 | 4.00266 | 1171.530 | -48.784 | 286.2 to 342.7 |
| Diethyl ether | C4H10O | 4.02200 | 1062.640 | -44.930 | 250.0 to 328.6 |
| Acetonitrile | C2H3N | 4.27873 | 1355.374 | -37.853 | 288.3 to 362.3 |
| Toluene | C7H8 | 4.07827 | 1343.943 | -53.773 | 308.5 to 384.7 |
| Tetrahydrofuran | C4H8O | 4.12118 | 1202.942 | -46.818 | 296.3 to 372.8 |
NIST Chemistry WebBook (webbook.nist.gov); Antoine coefficients calculated by NIST from the cited primary literature; form log10(P[bar]) = A - B/(T[K] + C).
Data revision 2026-06-22.
These values are imported from the same data the Aliquot calculators use, so this page cannot drift away from what the tools compute.