Gels

SDS-PAGE gel

Resolving & stacking gel recipes by acrylamide %.

recipe by %T
SDS-PAGE resolvingSDS-PAGE recipe
Calculated live

10% resolving gel, 10 mL total. Combine:

1

Mix the components below; add APS and TEMED last, then pour the gel immediately.

ComponentVolume
Deionised water3.963 mL
Acrylamide/bis 30% (29:1)3.333 mL
Tris buffer (1.5 M Tris-HCl pH 8.8)2.5 mL
SDS 10% (w/v)0.1 mL
APS 10% (w/v)0.1 mL
TEMED (neat)0.004 mL

Unpolymerised acrylamide is a potent neurotoxin, wear gloves, work in a fume hood, and handle as hazardous waste.

Add APS and TEMED last, they start polymerisation immediately. Make APS fresh (10% w/v aqueous) or store frozen in aliquots.

Acrylamide
10%
Layer
resolving
Volume
10 mL
SDS-PAGE gel, Aliquot