Undergraduate pharmacy

Pharmaceutical technology practical

Percent solutions, isotonicity, dose-response, and the hazard reference a formulation practical needs, with every step shown for the report.

10 calculators, in the order the course uses them. Every one shows its working, flags the hazards, and keeps working offline once the page has loaded. Free, and no account is needed.

Start with % concentration All topics and reference tables

In course order

What this practical calculates

1. % concentration

Convert %w/v, %w/w, %v/v ⇄ g/L and molarity.

How it works · Practice problems · %w/v · 10 = g/L

2. Simple dilution

C₁V₁ = C₂V₂, exactly how much stock and diluent to mix.

How it works · Practice problems · C₁ · V₁ = C₂ · V₂

3. Serial dilution

A fold-dilution series, tube by tube.

How it works · Practice problems · Cₙ = C₀ / fⁿ

4. Osmolarity

Total osmolarity of a multi-solute solution.

How it works · mOsm = sum(mM x particles)

5. Buffer / pH

Henderson-Hasselbalch, the acid/base split for a target pH.

How it works · Practice problems · pH = pKa + log₁₀([A⁻]/[HA])

6. Molarity, mass and volume conversion

Convert between molarity, mass, volume, and moles for a reagent, in any direction.

How it works · Practice problems · n = m / MW ; c = n / V

7. IC50 / EC50 (4PL fit)

Fit a dose-response curve and read off the IC50/EC50, Hill slope, and R².

How it works · y = D + (A − D) / (1 + (x/C)^B)

8. Standard curve

Fit a linear or quadratic standard curve (Bradford, BCA, ELISA) and read unknowns.

How it works · signal = slope x conc + intercept

9. NFPA 704 fire diamond

Build the health / flammability / instability / special hazard diamond.

How it works · NFPA 704 health / flammability / instability / special

10. Hydrate mass adjuster

Protocol assumes one hydrate, you have another? Get the corrected mass.

How it works · Practice problems · m_have = m_protocol · MW_have / MW_protocol

Worth telling students once

The mistakes this practical produces every year

A percentage by weight is not a percentage by volume. For a concentrated reagent the two differ by the density, which for 37% HCl is 19%.

Aliquot is an educational aid, not a compounding authority. Formulation work follows the pharmacopoeia and your institution’s protocols.

For the person running the course

If you want this page named for your course

What it costs

Nothing, for you and for your students, permanently. There is no licence to sign, no account for students to create, no data to hand over, and nothing for your IT department to approve or install.

What you would get

A page named for your course, with your calculations in your order and your conventions, at a stable URL you can paste into your course management system once and reuse every year.

What we would like back

To be told when it is wrong. If a value, a convention, or a hazard note does not match how your course teaches it, that is a bug worth fixing.

Ask for a page for your course

The honest caveat

Aliquot is an educational aid, not a safety authority and not a certified instrument. Students should verify critical values and follow the safety data sheet and your institution's protocols.

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